<\/p>\n
2020 \u00ebsht\u00eb tashm\u00eb duke e provuar veten si nj\u00eb vit gur\u00ebsh\u00ebnjues p\u00ebr shum\u00eb ar\u00ebsye, p\u00ebrfshir\u00eb edhe fush\u00ebn e mjek\u00ebsis\u00eb rigjeneruese. Nd\u00ebrsa qelizat staminale hematopoietike (HSC) t\u00eb gjendura n\u00eb gjakun e kordonit, munden, q\u00eb tani, t\u00eb trajtojn\u00eb mbi 85 s\u00ebmundje e probleme sh\u00ebndet\u00ebsore, terapi t\u00eb reja jan\u00eb n\u00eb zhvillim dhe n\u00eb faza provash klinike me nj\u00eb rit\u00ebm q\u00eb rritet me shpejt\u00ebsi, n\u00eb saj\u00eb t\u00eb avancimeve n\u00eb k\u00ebrkimet shkencore q\u00eb lidhen me qelizat staminale.<\/p>\n
A e dinit se, tashm\u00eb ka, atualisht, rreth 1,500 prova klinike q\u00eb po zhvillohen duke p\u00ebrdorur qelizat staminale hematopoietike HSC[1] dhe qelizat staminale mezhenchimale MSC[2] t\u00eb gjendura n\u00eb gjakun e kordonit k\u00ebrthizor? Me rritjen e k\u00ebtij numri, gjithnj\u00eb e m\u00eb shum\u00eb familje po zgjedhin ruajtjen n\u00eb bank\u00eb t\u00eb gjakut t\u00eb kordonit k\u00ebrthizor t\u00eb foshnj\u00ebs s\u00eb tyre n\u00eb momentin e lindjes. Ky burim i pasur i qelizave staminale mund t\u00eb ofroj\u00eb nj\u00eb mund\u00ebsi ‘rrug\u00ebdaljeje’ n\u00eb trajtimet mjek\u00ebsore t\u00eb ardhshme.<\/p>\n
Gjaku i kordonit k\u00ebrthizor dhe \u00e7rregullimet neurologjike<\/strong> N\u00eb m\u00ebnyr\u00eb t\u00eb ngjashme, qelizat staminale mezenchimale n\u00eb p\u00ebrb\u00ebrje t\u00eb indit t\u00eb kordonit k\u00ebrthizor (MSC)<\/a>, gjithashtu, e kan\u00eb treguar vetveten si \u2018t\u00eb sigurta dhe t\u00eb efektshme\u2019 p\u00ebr trajtimin e funksionit motor dhe gjith\u00ebp\u00ebrfshir\u00ebs n\u00eb pacient\u00ebt me paraliz\u00eb cerebrale. Kjo evidenc\u00eb e re terapeutike prej Shkurtit 2020[4] do t\u00eb veproj\u00eb tani si nj\u00eb pik\u00eb reference e \u00e7muar n\u00eb vijim\u00ebsin\u00eb e provave klinike.<\/p>\n \u00c7rregullimet n\u00eb Spektrin e Autizmit (ASD)<\/strong><\/em> Maksimi i’u n\u00ebnshtrua nj\u00eb terapie eksperimentale p\u00ebr autizmin duke p\u00ebrdorur qelizat staminale prej gjakut t\u00eb kordonit k\u00ebrthizor, t\u00eb cilin prind\u00ebrit e tij ja kishin ruajtur me nj\u00eb bank\u00eb private pas lindjes s\u00eb tij. Pas infuzionit fillestar dhe t\u00eb nj\u00eb infuzioni t\u00eb dyt\u00eb t\u00eb kryer me gjakun e kordonit nga motra e tij binjake, prind\u00ebrit e Maksimit vun\u00eb re p\u00ebrmir\u00ebsime t\u00eb mahnitshme n\u00eb aft\u00ebsit\u00eb komunikuese t\u00eb tij. Ju, mund t\u00eb lexoni t\u00eb plot\u00eb historin\u00eb e tij, k\u00ebtu<\/a>.<\/p>\n Gjaku i kordonit k\u00ebrthizor dhe koronavirusi (Covid-19)<\/strong> Nd\u00ebrsa ende nuk ka nj\u00eb evidenc\u00eb t\u00eb fort\u00eb rreth gjakut t\u00eb kordonit k\u00ebrthizor p\u00ebr trajtimin e Covid-19, nj\u00eb prov\u00eb e re klinike u lan\u00e7ua p\u00ebr t\u00eb investiguar nj\u00eb trajtim potencial me qelizat staminale mezenchimale t\u00eb nxjerra prej indit t\u00eb kordonit k\u00ebrthizor ( MSC ). Prova klinike, s\u00eb cil\u00ebs ju dha menj\u00ebher\u00eb drita e gjelb\u00ebr p\u00ebrmes nj\u00eb autorizimi p\u00ebrdorimi prej FDA, do t\u00eb nis\u00eb t\u00eb kryhet me 24 pacient\u00eb t\u00eb diagnostikuar me Covid-19 [6]. Lexoni k\u00ebtu artikullin e plot\u00eb t\u00eb mbulimit t\u00eb k\u00ebsaj prove klinike<\/a>.<\/p>\n Gjaku i kordonit k\u00ebrthizor dhe \u00e7rregullimet e gjakut<\/strong> Leu\u00e7emia Akute Limfoblastike<\/strong><\/em> Anemia Aplastike<\/strong><\/em> Referenca: P\u00ebr t\u00eb sh\u00ebnjuar Muajin e Nd\u00ebrgjegj\u00ebsimit t\u00eb Ruajtjes s\u00eb Gjakut t\u00eb Kordonit K\u00ebrthizor dhe fillimin e nj\u00eb dekade t\u00eb re, Future Health Biobank, hodhi nj\u00eb v\u00ebshtrim mbi at\u00eb se si qelizat staminale prej gjakut t\u00eb kordonit jan\u00eb duke e transformuar sh\u00ebndetin ton\u00eb me ndihm\u00ebn e ruajtjes n\u00eb bank\u00eb t\u00eb gjakut t\u00eb kordonit k\u00ebrthizor.<\/p>\n","protected":false},"author":25,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[216,218],"tags":[],"class_list":["post-10045","post","type-post","status-publish","format-standard","hentry","category-perditesime-klinike","category-te-reja-nga-ne"],"acf":[],"yoast_head":"\n
\nParaliza Cerebrale<\/em><\/strong>
\nS\u00eb fundi, Future Health Biobank, l\u00ebshoi kampionin e gjakut t\u00eb kordonit k\u00ebrthizor t\u00eb nj\u00eb klienti t\u00eb saj p\u00ebr t\u00eb ndihmuar n\u00eb trajtimin e paraliz\u00ebs cerebrale<\/a>. Prova klinike pioniere n\u00eb llojin e saj u krye pran\u00eb Duke University[3] me nj\u00eb vajz\u00eb trevje\u00e7are t\u00eb diagnostikuar me paraliz\u00eb cerebrale (CP), duke p\u00ebrdorur qelizat staminale t\u00eb gjakut t\u00eb kordonit t\u00eb ruajtura pas lindjes s\u00eb v\u00ebllait t\u00eb saj. Deri m\u00eb tani kjo prov\u00eb klinike ka demonstruar se nj\u00eb infuzion i qelizave staminale prej gjakut t\u00eb kordonit k\u00ebrthizor mundet t\u00eb p\u00ebrmir\u00ebsoj\u00eb funksionin motor n\u00eb pacient\u00ebt me paraliz\u00eb cerebrale.<\/p>\n
\nRreth 700,000 njer\u00ebz n\u00eb Mbret\u00ebrin\u00eb e Bashkuar vuajn\u00eb probleme t\u00eb spektrit t\u00eb Autizmit, \u00e7ka i takon mbi 1 n\u00eb 100[5]. Nd\u00ebrkoh\u00eb q\u00eb nuk ka ndonj\u00eb kur\u00eb p\u00ebr t\u00eb, qelizat staminale t\u00eb gjakut t\u00eb kordonit k\u00ebrthizor jan\u00eb n\u00eb faz\u00eb provash klinike p\u00ebr t\u00eb mund\u00ebsuar menaxhimin e simptomave. Rezultatet kan\u00eb qen\u00eb mjaft premtuese n\u00eb nj\u00eb num\u00ebr f\u00ebmij\u00ebsh n\u00eb mosh\u00eb t\u00eb re, p\u00ebrfshir\u00eb rastin e Maksimit pes\u00ebvje\u00e7ar nga Ukraina.<\/p>\n
\nNd\u00ebrsa pandemija e Covid-19 paraqet nj\u00eb rrezik t\u00eb menj\u00ebhersh\u00ebm, shkenc\u00ebtar\u00ebt edhe nj\u00ebher\u00eb po i rikthehen qelizat staminale t\u00eb gjakut t\u00eb kordonit k\u00ebrthizor. Prova klinike mjaft premtuese jan\u00eb duke u kryer n\u00eb Azi, Europ\u00eb dhe n\u00eb Shtetet e Bashkuara, duke investiguar n\u00ebse qelizat staminale hematopoietike HSC dhe qelizat staminale mezenchimale MSC do t\u00eb mund t\u00eb trajtojn\u00eb sindrom\u00ebn e distresit akut respirator(ARDS), e cila \u00ebsht\u00eb shpesh nj\u00eb komplikacion fatal i COVID-19.<\/p>\n
\nQelizat staminale hematopoietike t\u00eb gjakut t\u00eb kordonit (HSC ) ofrojn\u00eb tashm\u00eb terapi standarde p\u00ebr trajtimin e nj\u00eb game t\u00eb gj\u00ebr\u00eb \u00e7rregullimesh t\u00eb trash\u00ebguara t\u00eb gjakut dhe q\u00eb lidhen me gjakun. Dy prej \u00e7rregullimeve m\u00eb dometh\u00ebn\u00ebse e m\u00eb t\u00eb r\u00ebnda jan\u00eb llojet e Leu\u00e7emis\u00eb dhe ato t\u00eb Anemis\u00eb.<\/p>\n
\nNd\u00ebrsa kjo form\u00eb e leu\u00e7emis\u00eb \u00ebsht\u00eb e rall\u00eb, ajo mund t\u00eb kurohet me nj\u00eb infuzion qelizash staminale hematopoietike prej gjakut t\u00eb kordonit k\u00ebrthizor HSC. N\u00eb Qershor 2019, nj\u00eb bebe mashkull i diagnostikuar n\u00eb lindje me Leu\u00e7emi limfoblastike arriti t\u00eb shp\u00ebtonte pas nj\u00eb trajtimi t\u00eb sukssesh\u00ebm me nj\u00eb terapi qelizash staminale duke p\u00ebrdorur gjakun e kordonit k\u00ebrthizor t\u00eb dhuruar. E p\u00ebrdorur n\u00eb kombinim me kemioterapin\u00eb, terapia e Harrit rezultoi 100% e suksesshme. Ju, mund ta lexoni historin\u00eb e plot\u00eb, k\u00ebtu<\/a>.<\/p>\n
\nHenrique kat\u00ebrvje\u00e7ar vuante prej Anemis\u00eb Aplastike e cila ishte k\u00ebrc\u00ebnuese p\u00ebr jet\u00ebn. N\u00eb saj\u00eb t\u00eb gjakut t\u00eb kordonit k\u00ebrthizor, qelizat staminale t\u00eb kordonit t\u00eb ruajtura prej vet\u00eb atij menj\u00ebher\u00eb pas lindjes, u p\u00ebrdor\u00ebn p\u00ebr trajtimin e tij n\u00eb nj\u00eb spital n\u00eb Portugali. Qelizat staminale u p\u00ebrdor\u00ebn p\u00ebr t\u00eb z\u00ebvend\u00ebsuar qelizat e gjakut t\u00eb d\u00ebmtuara t\u00eb Henriques, e m\u00eb pas ato u riprodhuan p\u00ebr t\u00eb rifituar nj\u00eb num\u00ebr t\u00eb konsideruesh\u00ebm qelizash t\u00eb sh\u00ebndetshme t\u00eb gjakut dhe funksionin e sistemit imunitar t\u00eb tij. Anemia aplastike \u00ebsht\u00eb nj\u00ebra prej 85 s\u00ebmundjeve t\u00eb cilat trajtohen aktualisht n\u00eb m\u00ebnyr\u00eb standarde duke p\u00ebrdorur qelizat staminale hematopoietike prej gjakut t\u00eb kordonit k\u00ebrthizor (HSC ). Ju mund ta lexoni historin\u00eb e plot\u00eb, k\u00ebtu<\/a>.<\/p>\n
\n[1] https:\/\/clinicaltrials.gov\/<\/a>
\n[2] https:\/\/clinicaltrials.gov\/<\/a>
\n[3] https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03473301<\/a>
\n[4] https:\/\/pubmed.ncbi.nlm.nih.gov\/<\/a>
\n[5] https:\/\/www.autism.org.uk\/<\/a>
\n[6] https:\/\/www.newswise.com\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"