{"id":9673,"date":"2018-11-26T16:56:56","date_gmt":"2018-11-26T15:56:56","guid":{"rendered":"https:\/\/futurehealthbiobank.com\/al\/?p=9673"},"modified":"2018-11-26T16:56:56","modified_gmt":"2018-11-26T15:56:56","slug":"a-do-te-munden-qelizat-staminale-prej-kordonit-kerthizor-te-ndihmojne-pacientet-me-lupus","status":"publish","type":"post","link":"https:\/\/futurehealthbiobank.com\/al\/blog\/a-do-te-munden-qelizat-staminale-prej-kordonit-kerthizor-te-ndihmojne-pacientet-me-lupus\/","title":{"rendered":"A do t\u00eb munden Qelizat Staminale prej Kordonit K\u00ebrthizor t\u00eb Ndihmojn\u00eb Pacient\u00ebt me Lupus?"},"content":{"rendered":"

Nj\u00eb prov\u00eb e re klinike e faz\u00ebs 1 ka zhvilluar hetime rreth Qelizave Staminale Mezenchimale t\u00eb nxjerra prej Kordonit K\u00ebrthizor mbi efektin q\u00eb mund t\u00eb ken\u00eb ato mbi sistemin imunitar t\u00eb pacient\u00ebve me Lupus. Megjith\u00ebse studimi ishte n\u00eb p\u00ebrmasa t\u00eb vogla, u v\u00ebrejt\u00ebn rezultate mjaft pozitive 24 jav\u00eb pas trajtimit me to.<\/h3>\n

<\/p>\n

Gjat\u00eb prov\u00ebs klinike pran\u00eb Universitetit Mjek\u00ebsor t\u00eb Karolin\u00ebs s\u00eb Jugut, gjasht\u00eb pacient\u00ebve me Eritematoz\u00eb refraktare t\u00eb Lupusit Sistemik (SLE) ju dha nj\u00eb injeksion Qelizash Staminale Mezenchimale t\u00eb nxjerra prej kordonit k\u00ebrthizor. Shkenc\u00ebtar\u00ebt mat\u00ebn at\u00eb se si ky infuzion trajtoi sistemin imunitar t\u00eb pacient\u00ebve. N\u00eb ve\u00e7anti, ata u p\u00ebrq\u00ebndruan mbi llojet e qelizave T dhe qelizat B t\u00eb cilat ndikojn\u00eb\/pengojn\u00eb funksionimin e sistemit imunitar tek t\u00eb s\u00ebmur\u00ebt me Lupus.<\/p>\n

24 jav\u00eb pas trajtimit, Qelizat Staminale Mezenchimale(MSC) treguan se ndihmonin n\u00eb rregullimin e aktivitetit t\u00eb qelizave B dhe n\u00eb autoimunitetin. Qelizat staminale n\u00eb m\u00ebnyr\u00eb t\u00eb dukshme zvog\u00ebluan numrin e qelizave B anormale dhe rrit\u00ebn qelizat B joreaguese n\u00eb kat\u00ebr prej gjasht\u00eb pacient\u00ebve. N\u00eb dy pacient\u00eb, trajtimi me qelizat staminale u shoq\u00ebrua me nj\u00eb rritje t\u00eb leht\u00eb n\u00eb qelizat T.<\/p>\n

Qelizat staminale mezenchimale(MSCs) gjenden n\u00eb indin e kordonit k\u00ebrthizor. Ato munden t\u00eb shumohen dhe t\u00eb formojn\u00eb k\u00ebrce, kocka dhe inde dhjamor. Kjo prov\u00eb klinike n\u00eb faz\u00ebn e par\u00eb<\/strong><\/a> sugjeron se prej nj\u00eb infuzioni me qeliza staminale mezenchimale mund t\u00eb p\u00ebrfitojn\u00eb drejtp\u00ebrdrejt rastet me Lupus t\u00eb cil\u00ebt jan\u00eb t\u00eb v\u00ebshtir\u00eb p\u00ebr t’u trajtuar, megjith\u00ebse nj\u00eb prov\u00eb klinike e faz\u00ebs 2 \u00ebsht\u00eb lan\u00e7uar tashm\u00eb p\u00ebr t\u00eb hetuar m\u00eb n\u00eb thell\u00ebsi rreth k\u00ebtyre zbulimeve.<\/p>\n

N\u00eb prov\u00ebn klinike t\u00eb faz\u00ebs 2, hulumtuesit do t\u00eb zhvillojn\u00eb nj\u00eb prov\u00eb klinike dyfish t\u00eb anonimizuar, t\u00eb kontrolluar me placebo – n\u00eb shtes\u00eb t\u00eb kujdesit standard p\u00ebr Lupusin n\u00eb 81 adult\u00eb. Pacient\u00ebt do t\u00eb kryhen n\u00eb m\u00ebnyr\u00eb rast\u00ebsore p\u00ebr t\u00eb marr\u00eb nj\u00eb ose dy infuzione me Qeliza Staminale Mezenchimale ose nj\u00eb placebo. P\u00ebr t\u00eb p\u00ebrcaktuar suksesin, hulumtuesit do t\u00eb v\u00ebzhgojn\u00eb p\u00ebr t\u00eb gjetur nj\u00eb reduktim prej kat\u00ebr pik\u00ebsh ose m\u00eb shum\u00eb, sipas sistemit t\u00eb Indeksit t\u00eb Aktivitetit t\u00eb S\u00ebmundjes s\u00eb Eritematoz\u00ebs s\u00eb Lupusit Sistemik (SLEDAI), si edhe t\u00eb frekuenc\u00ebs s\u00eb rishfaqjes s\u00eb s\u00ebmundjes, deboles\u00ebs, dhimbjes dhe depresionit.<\/p>\n

Shpresohet se pasi t\u00eb ket\u00eb p\u00ebrfunduar edhe prova klinike e Faz\u00ebs 2, ne do t\u00eb mundemi t\u00eb kuptojm\u00eb efektshm\u00ebrin\u00eb dhe sigurin\u00eb e p\u00ebrdorimit t\u00eb qelizave staminale mezenchimale p\u00ebr trajtimin n\u00eb t\u00eb ardhmen t\u00eb Lupusit.<\/p>\n

Referenca:\u00a0lupusnewstoday.com<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Nj\u00eb prov\u00eb e re klinike e faz\u00ebs 1 ka zhvilluar hetime rreth Qelizave Staminale Mezenchimale t\u00eb nxjerra prej Kordonit K\u00ebrthizor mbi efektin q\u00eb mund t\u00eb ken\u00eb ato mbi sistemin imunitar t\u00eb pacient\u00ebve me Lupus. Megjith\u00ebse studimi ishte n\u00eb p\u00ebrmasa t\u00eb vogla, u v\u00ebrejt\u00ebn rezultate mjaft pozitive 24 jav\u00eb pas trajtimit me to.<\/p>\n","protected":false},"author":25,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[216],"tags":[],"class_list":["post-9673","post","type-post","status-publish","format-standard","hentry","category-perditesime-klinike"],"acf":[],"yoast_head":"\nA do t\u00eb munden Qelizat Staminale prej Kordonit K\u00ebrthizor t\u00eb Ndihmojn\u00eb Pacient\u00ebt me Lupus? | Future Health Biobank<\/title>\n<meta name=\"description\" content=\"Nj\u00eb prov\u00eb e re klinike e faz\u00ebs 1 ka zhvilluar hetime rreth Qelizave Staminale Mezenchimale t\u00eb nxjerra prej Kordonit K\u00ebrthizor mbi efektin q\u00eb mund t\u00eb ken\u00eb ato mbi sistemin imunitar t\u00eb pacient\u00ebve me Lupus. 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