{"id":7531,"date":"2018-01-18T09:28:48","date_gmt":"2018-01-18T09:28:48","guid":{"rendered":"https:\/\/futurehealthbiobank.com\/ba\/?p=7531"},"modified":"2018-01-30T15:39:43","modified_gmt":"2018-01-30T15:39:43","slug":"zubni-karijes-bi-se-mogao-tretirati-maticnim-celijama-iz-dentalne-pulpe","status":"publish","type":"post","link":"https:\/\/futurehealthbiobank.com\/ba\/blog\/zubni-karijes-bi-se-mogao-tretirati-maticnim-celijama-iz-dentalne-pulpe\/","title":{"rendered":"Zubni karijes bi se mogao tretirati mati\u010dnim \u0107elijama iz dentalne pulpe"},"content":{"rendered":"

Nau\u010dnici dvije laboratorije iz Kine daju nadu ljudima koji imaju problema sa karijesom. Istra\u017eivanja su pokazala da \u0107elije dentane pulpe imaju mogu\u0107nost regeneracije zubnog tkiva.<\/h3>\n

<\/p>\n

Istra\u017eivanje objavljeno u STEM CELLS Translational Medicine pokazalo je da se prilikom modifikacije dentalne pulpe prekomjerno izra\u017eava faktor rasta razvijenih krvnih plo\u010dica-BB(PDGF-BB), \u010dime \u0107elije zna\u010dajno pobolj\u0161avaju regeneraciju tkiva.<\/p>\n

Iako mati\u010dne \u0107elije dentalne pulpe nisu u mogu\u0107nosti da obnove zub direktno, ovo bi mogla biti nova prekretnica koja bi sprije\u010dila bol koju uzrokuje zubobolja. Prvo, autori studije transduciraju multipotentne, dentalne mati\u010dne \u0107elije u ranom razvoju (hDPSCs) sa PDGF-BB ekspresionim vektorom. Ove generirane \u0107elije su pokazale pove\u0107anu proliferaciju i pove\u0107an nivo odontogenih marker gena- koji su uklju\u010deni u razvoj zuba. Modifikovane mati\u010dne \u0107elije tako\u0111er se zaka\u010de i \u0161ire dobro na povr\u0161ini kalcijevog-fosfatng cementa(CPC) koji se koristi za implementaciju.<\/p>\n

PDGF-BB modifikovane \u0107elije generiraju vi\u0161e dentin-mineraliziranog tkiva koji je okru\u017een visoko vaskulariziranim vezivnim tkivom dentalne pulpe u 12 sedmici kada se uporedi sa nemodifikovanim hDPSCs.<\/p><\/blockquote>\n

– Zhang, W et al., Shanghai Jiao Tong University\u00a0<\/cite><\/p>\n

Kliknite ovdje za vi\u0161e rezultata vezanih za studiju o dentalnim mati\u010dnim \u0107elijama<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Nau\u010dnici dvije laboratorije iz Kine daju nadu ljudima koji imaju problema sa karijesom. Istra\u017eivanja su pokazala da \u0107elije dentane pulpe imaju mogu\u0107nost regeneracije zubnog tkiva.<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[218],"tags":[],"class_list":["post-7531","post","type-post","status-publish","format-standard","hentry","category-klinicko-azuriranje"],"acf":[],"yoast_head":"\nZubni karijes bi se mogao tretirati mati\u010dnim \u0107elijama iz dentalne pulpe | Future Health Biobank<\/title>\n<meta name=\"description\" content=\"Nau\u010dnici dvije laboratorije iz Kine daju nadu ljudima koji imaju problema sa karijesom. 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