BioEden - Tooth Stem Cell Bank

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FREQUENTLY ASKED QUESTIONS

What are dental pulp stem cells?

The term ‘tooth stem cells’ refers to specialist stem cells found in the soft tissue at the centre of a tooth, the dental pulp. Milk teeth that naturally fall out contain a rich source of cells, known as mesenchymal stem cells (MSCs). This type of stem cell can repair and repair many types of tissue in the body, including muscle, nerve, bone and cartilage, to treat diseases.

What is dental pulp banking?

Tooth stem cell banking starts with collecting a single fallen milk tooth from your child, then having the stem cells processed and stored for use in potential future treatments. All our samples are stored privately, meaning the stem cells will only be accessible to your child and/or a family member.

What diseases can dental pulp stem cells currently treat?

Mesenchymal stem cells found in teeth are currently present in many studies worldwide. These trials have identified the benefits of tooth stem cells for treating a range of illnesses such as muscular dystrophy, neurogenerative diseases and arthritis.

Acquisition of BioEden by Future Health Group

Where are your offices based?

After the successful acquisition of BioEden by Future Health Group, our customer care department are now based at our headquarters in Nottingham, United Kingdom. Our team consists of both English and Spanish speaking customer care advisors.

Clinical trials

When the term “Dental pulp stem cells” is searched at the clinicaltrials.gov website, 27 clinical trial reports appear. Some examples that showcase the diversity of the applications include:

1. Bone tissue engineering with dental pulp stem cells for alveolar cleft repair NCT03766217
2. Clinical study of pulp mesenchymal stem cells in the treatment of primary mild to moderate knee osteoarthritis NCT04130100
3. Stem cells from human exfoliated teeth in treatment of diabetic patients with significantly reduced islet function NCT03912480
4. Pilot trial of mesenchymal stem cells (including DPSCs) for systemic lupus erythematosus
5. Periodontal regeneration using dental pulp stem cells NCT03386877
6. Feasibility of the preparation of an advanced therapy medicinal product for dental pulp regeneration NCT02842515
7. Dose-response evaluation of the Cellavita HD product in patients with Huntington’s disease NCT03252535

How long can tooth stem cells be stored for?

One of the defining characteristics of stem cells is their ability to turn into other cell types in the body, allowing the body to use these cells to repair and regenerate tissues.

This process of stem cells turning into other cell types is called differentiation.

Our in-house team of R&D scientists are conducting ongoing studies into the viability of tooth stem cells which have been in long-term cryogenic storage.

We have successfully thawed, cultured and differentiated tooth cells that were cryopreserved in 2012*. This data suggests they will behave like other stem cells that have been in long-term cryogenic storage which have successfully been used for transplant.

The work is ongoing both in-house and amongst the scientific community to demonstrate that, as with cord blood stem cells, tooth cells which have been in long-term cryogenic storage remain viable for use in transplants.

*Data from 2022

If we need to use our sample, what is the process?

Should you ever need to use your tooth stem cell sample, please email our team at customercare@bioeden.com, with as much information as possible, and we will discuss with you the next steps.