{"id":10142,"date":"2019-02-26T15:18:09","date_gmt":"2019-02-26T14:18:09","guid":{"rendered":"https:\/\/futurehealthbiobank.com\/ch-en\/?p=10142"},"modified":"2020-06-23T11:44:43","modified_gmt":"2020-06-23T09:44:43","slug":"cord-blood-stem-cell-transplant-corrects-irritable-bowel-disease","status":"publish","type":"post","link":"https:\/\/futurehealthbiobank.com\/ch-en\/blog\/cord-blood-stem-cell-transplant-corrects-irritable-bowel-disease\/","title":{"rendered":"Cord Blood Stem Cell Transplant Corrects Irritable Bowel Disease"},"content":{"rendered":"<h3>A baby girl, Zhao Jiaxin, has become the first child in China to receive a cord blood stem cell transplant to cure an inherited type of Irritable Bowel Disease.<\/h3>\n<p><!--more--><\/p>\n<p><a href=\"https:\/\/futurehealthbiobank.com\/ch-en\/wp-content\/uploads\/sites\/19\/2019\/02\/zhao-cord-blood-story.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter size-medium wp-image-12524\" src=\"https:\/\/futurehealthbiobank.com\/ch-en\/wp-content\/uploads\/sites\/19\/2019\/02\/zhao-cord-blood-story-300x208.jpg\" alt=\"Zhao\" width=\"300\" height=\"208\" srcset=\"https:\/\/futurehealthbiobank.com\/ch-en\/wp-content\/uploads\/sites\/19\/2019\/02\/zhao-cord-blood-story-300x208.jpg 300w, https:\/\/futurehealthbiobank.com\/ch-en\/wp-content\/uploads\/sites\/19\/2019\/02\/zhao-cord-blood-story.jpg 360w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a><\/p>\n<p>When Zhao was born in 2015, she started suffering from fever and diarrhoea from just 8 days old. Her older sister had the same symptoms and tragically died at 5 months old, so her parents feared they might lose Zhao too. So, they turned to the Children\u2019s Hospital of Fudan University in Shanghai.<\/p>\n<p>At the University, the family found out that Zhao had a Very Early Onset form of Irritable Bowel Disease (VEO-IBS); a rare condition caused by an inherited genetic mutation. The deficiency in the defective gene led to severe problems with Zhao\u2019s immune system, which cause malnourishment, intestinal abscesses and fistulas.<\/p>\n<blockquote><p>The only effective treatment is a stem cell transplant\u2026 It can help to repair the genetic deformity and control the symptoms of the disease<\/p><\/blockquote>\n<p><cite>&#8211; Huang Ying, MD PhD, Children\u2019s Hospital of Fudan University<\/cite><\/p>\n<p>In 2015, Zhao became one of very few babies to receive a cord blood stem cell transplant for VEO-IBS with IL10RA immune deficiency. The successful transplants were carried out using low-intensity chemotherapy conditioning, with positive results within 1-3 months. Thanks to this pioneering transplant, Zhao\u2019s condition has improved greatly and she should lead a happy, healthy life.<\/p>\n<p>Reference: <a href=\"https:\/\/parentsguidecordblood.org\/en\/news\/cord-blood-transplant-corrects-very-early-onset-irritable-bowel-disease\">parentsguidecordblood.org\/<\/a><\/p>\n<div class=\"helpful-block-content wth-theme-thumbs\" data-title=\"\" >\n<ul>\n<li><span class=\"wth-title\">Was this Helpful?<\/span><\/li>\n<li><a data-post=\"10142\" data-post-url=\"https:\/\/futurehealthbiobank.com\/ch-en\/blog\/cord-blood-stem-cell-transplant-corrects-irritable-bowel-disease\/\" data-post-title=\"Cord Blood Stem Cell Transplant Corrects Irritable Bowel Disease\" data-response=\"1\" href=\"#\" class=\"wth-green-btn icon-thumbsup icon1-thumbs-up4\">Yes<\/a><a data-response=\"0\" data-post=\"10142\" data-post-url=\"https:\/\/futurehealthbiobank.com\/ch-en\/blog\/cord-blood-stem-cell-transplant-corrects-irritable-bowel-disease\/\" data-post-title=\"Cord Blood Stem Cell Transplant Corrects Irritable Bowel Disease\" href=\"#\" class=\"wth-red-btn icon-thumbsdown icon1-thumbs-down4\">No<\/a><\/li>\n<\/ul>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>A baby girl, Zhao Jiaxin, has become the first child in China to receive a cord blood stem cell transplant to cure an inherited type of Irritable Bowel Disease. Was this Helpful? YesNo<\/p>\n","protected":false},"author":10,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[221],"tags":[],"class_list":["post-10142","post","type-post","status-publish","format-standard","hentry","category-clinical-update"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.7 (Yoast SEO v26.7) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cord Blood Stem Cell Transplant Corrects Irritable Bowel Disease | Future Health Biobank<\/title>\n<meta name=\"description\" content=\"A baby girl, Zhao Jiaxin, has become the first child in China to receive a cord blood stem cell transplant to cure an inherited type of Irritable Bowel Disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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