{"id":7592,"date":"2018-02-09T15:18:55","date_gmt":"2018-02-09T15:18:55","guid":{"rendered":"https:\/\/futurehealthbiobank.com\/ua\/?p=7592"},"modified":"2018-02-09T16:05:06","modified_gmt":"2018-02-09T16:05:06","slug":"umbilical-cord-liver-transplant-rejection","status":"publish","type":"post","link":"https:\/\/futurehealthbiobank.com\/ua\/blog\/umbilical-cord-liver-transplant-rejection\/","title":{"rendered":"\u0421\u0442\u043e\u0432\u0431\u0443\u0440\u043e\u0432\u0456 \u043a\u043b\u0456\u0442\u0438\u043d\u0438 \u043f\u0443\u043f\u043e\u0432\u0438\u043d\u0438 \u043c\u043e\u0436\u0443\u0442\u044c \u0437\u0430\u043f\u043e\u0431\u0456\u0433\u0442\u0438 \u0432\u0456\u0434\u0442\u043e\u0440\u0433\u043d\u0435\u043d\u043d\u044e \u043f\u0440\u0438 \u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0446\u0456\u0457 \u043f\u0435\u0447\u0456\u043d\u043a\u0438"},"content":{"rendered":"<h3>\u0417\u0430 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0430\u043c\u0438 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\u043b\u0438\u0441\u0442\u043e\u043f\u0430\u0434\u0430 2017 \u0440\u043e\u043a\u0443. \u0419\u0448\u043b\u043e\u0441\u044f \u043f\u0440\u043e \u0432\u0438\u043a\u043e\u0440\u0438\u0441\u0442\u0430\u043d\u043d\u044f \u043c\u0435\u0437\u0435\u043d\u0445\u0456\u043c\u0430\u043b\u044c\u043d\u0438\u0445 \u0441\u0442\u043e\u0432\u0431\u0443\u0440\u043e\u0432\u0438\u0445 \u043a\u043b\u0456\u0442\u0438\u043d \u043f\u0443\u043f\u043e\u0432\u0438\u043d\u0438, \u044f\u043a\u0456 \u0437\u0434\u0430\u0442\u043d\u0456 \u043f\u0435\u0440\u0435\u0442\u0432\u043e\u0440\u044e\u0432\u0430\u0442\u0438\u0441\u044c \u043d\u0430 \u0440\u0456\u0437\u043d\u0456 \u0442\u0438\u043f\u0438 \u043a\u043b\u0456\u0442\u0438\u043d.<\/p>\n<p>\u041e\u0442\u0440\u0438\u043c\u0430\u043d\u0456 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0438 \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0438, \u0449\u043e UC-MSC \u0437\u043c\u043e\u0433\u043b\u0438 \u043f\u0440\u0438\u043f\u0438\u043d\u0438\u0442\u0438 &#8220;\u0433\u043e\u0441\u0442\u0440\u0438\u0439 \u0430\u043b\u043b\u043e\u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0442&#8221;, \u0442\u043e\u0431\u0442\u043e \u0432\u0456\u0434\u0442\u043e\u0440\u0433\u043d\u0435\u043d\u043d\u044f \u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u043e\u0432\u0430\u043d\u043e\u0457 \u043f\u0435\u0447\u0456\u043d\u043a\u0438 \u0443 14 \u043f\u0430\u0446\u0456\u0454\u043d\u0442\u0456\u0432, \u0437\u0430\u0432\u0434\u044f\u043a\u0438 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0456\u0457 \u0456\u043c\u0443\u043d\u043d\u043e\u0457 \u0441\u0438\u0441\u0442\u0435\u043c\u0438 \u0434\u043e \u043f\u0440\u0438\u0439\u043d\u044f\u0442\u0442\u044f \u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0442\u0430. \u0416\u043e\u0434\u043d\u0438\u0445 \u043f\u043e\u0431\u0456\u0447\u043d\u0438\u0445 \u0435\u0444\u0435\u043a\u0442\u0456\u0432 \u0432\u0438\u044f\u0432\u043b\u0435\u043d\u043e \u043d\u0435 \u0431\u0443\u043b\u043e. \u041e\u0442\u0436\u0435, \u0432\u0438\u0441\u043d\u043e\u0432\u043e\u043a, \u0449\u043e \u043f\u0456\u0441\u043b\u044f \u043f\u043e\u0434\u0430\u043b\u044c\u0448\u0438\u0445 \u0432\u0438\u043f\u0440\u043e\u0431\u0443\u0432\u0430\u043d\u044c, UC-MSCs \u043c\u043e\u0436\u043d\u0430 \u0432\u0438\u043a\u043e\u0440\u0438\u0441\u0442\u043e\u0432\u0443\u0432\u0430\u0442\u0438 \u0434\u043b\u044f \u0437\u043c\u0435\u043d\u0448\u0435\u043d\u043d\u044f \u043a\u0456\u043b\u044c\u043a\u043e\u0441\u0442\u0456 \u0432\u0438\u043f\u0430\u0434\u043a\u0456\u0432 \u0432\u0456\u0434\u0442\u043e\u0440\u0433\u043d\u0435\u043d\u043d\u044f.<\/p>\n<p>\u0414\u0430\u043d\u0435 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f \u0441\u043f\u0440\u044f\u043c\u043e\u0432\u0430\u043d\u0435 \u043d\u0430 \u043e\u0446\u0456\u043d\u043a\u0443 \u0431\u0435\u0437\u043f\u0435\u043a\u0438 \u0442\u0430 \u043a\u043b\u0456\u043d\u0456\u0447\u043d\u043e\u0457 \u0434\u043e\u0446\u0456\u043b\u044c\u043d\u043e\u0441\u0442\u0456 \u0442\u0435\u0440\u0430\u043f\u0456\u0457 \u0437 \u0432\u0438\u043a\u043e\u0440\u0438\u0441\u0442\u0430\u043d\u043d\u044f\u043c \u043c\u0435\u0437\u0435\u043d\u0445\u0456\u043c\u0430\u043b\u044c\u043d\u0438\u0445 \u0441\u0442\u043e\u0432\u0431\u0443\u0440\u043e\u0432\u0438\u0445 \u043a\u043b\u0456\u0442\u0438\u043d (UC-MSCS), \u043e\u0442\u0440\u0438\u043c\u0430\u043d\u0438\u0445 \u0437 \u043f\u0443\u043f\u043e\u0432\u0438\u043d\u0438, \u0434\u043b\u044f \u043f\u0430\u0446\u0456\u0454\u043d\u0442\u0456\u0432 \u0456\u0437 \u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0446\u0456\u0454\u044e \u043f\u0435\u0447\u0456\u043d\u043a\u0438 \u0442\u0430 \u0456\u0437 \u0433\u043e\u0441\u0442\u0440\u0438\u043c \u0432\u0456\u0434\u0442\u043e\u0440\u0433\u043d\u0435\u043d\u043d\u044f\u043c \u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0442\u0456\u0432. \u041d\u0456\u044f\u043a\u0438\u0445 \u0443\u0441\u043a\u043b\u0430\u0434\u043d\u0435\u043d\u044c \u0430\u0431\u043e \u043f\u043e\u0431\u0456\u0447\u043d\u0438\u0445 \u0435\u0444\u0435\u043a\u0442\u0456\u0432 \u043d\u0435 \u0441\u043f\u043e\u0441\u0442\u0435\u0440\u0456\u0433\u0430\u043b\u043e\u0441\u044f. \u0422\u0435\u0440\u0430\u043f\u0456\u044f UC-MSC \u043c\u043e\u0436\u0435 \u0437\u043c\u0435\u043d\u0448\u0438\u0442\u0438 \u043f\u043e\u0448\u043a\u043e\u0434\u0436\u0435\u043d\u043d\u044f \u043f\u0435\u0447\u0456\u043d\u043a\u0438 \u0442\u0430 \u043f\u043e\u043a\u0440\u0430\u0449\u0438\u0442\u0438 \u0433\u0456\u0441\u0442\u043e\u043b\u043e\u0433\u0456\u044e \u0430\u043b\u043b\u043e\u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0442\u0443. \u041a\u0440\u0456\u043c \u0442\u043e\u0433\u043e, \u043f\u0456\u0441\u043b\u044f \u0442\u0440\u0430\u043d\u0441\u0444\u0443\u0437\u0456\u0457 UC-MSC \u0437\u043d\u0430\u0447\u043d\u043e \u043f\u0456\u0434\u0432\u0438\u0449\u0438\u043b\u0430\u0441\u044f \u043f\u0435\u0440\u0438\u0444\u0435\u0440\u0438\u0447\u043d\u0430 \u0447\u0430\u0441\u0442\u043e\u0442\u0430 \u0440\u0435\u0433\u0443\u043b\u044f\u0442\u043e\u0440\u043d\u0438\u0445 \u0422-\u043a\u043b\u0456\u0442\u0438\u043d (Tregs), \u0441\u043f\u0456\u0432\u0432\u0456\u0434\u043d\u043e\u0448\u0435\u043d\u043d\u044f Treg \/ T-\u0434\u043e\u043f\u043e\u043c\u0456\u0436\u043d\u0438\u0445 17 (Th17) \u043a\u043b\u0456\u0442\u0438\u043d \u0442\u0430 \u0440\u0456\u0432\u043d\u0456\u0432 \u0441\u0438\u0440\u043e\u0432\u0430\u0442\u043a\u043e\u0432\u043e\u0433\u043e \u0442\u0440\u0430\u043d\u0441\u0444\u043e\u0440\u043c\u0443\u044e\u0447\u043e\u0433\u043e \u0444\u0430\u043a\u0442\u043e\u0440\u0430 \u0440\u043e\u0441\u0442\u0443 \u0431\u0435\u0442\u0430-1 \u0442\u0430 \u043f\u0440\u043e\u0441\u0442\u0430\u0433\u043b\u0430\u043d\u0434\u0438\u043d\u0443 \u04152. &#8211; \u041c\u0456\u043d \u0428\u0456, \u041d\u0430\u0443\u043a\u043e\u0432\u0438\u0439 \u0446\u0435\u043d\u0442\u0440 \u0431\u0456\u043e\u043b\u043e\u0433\u0456\u0447\u043d\u043e\u0457 \u0442\u0435\u0440\u0430\u043f\u0456\u0457, \u041f\u0435\u043a\u0456\u043d<\/p>\n<p><strong><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/sctm.17-0134\/full\">\u041d\u0430\u0442\u0438\u0441\u043d\u0456\u0442\u044c \u0442\u0443\u0442, \u0449\u043e\u0431 \u043f\u043e\u0432\u043d\u0456\u0441\u0442\u044e \u043e\u0437\u043d\u0430\u0439\u043e\u043c\u0438\u0442\u0438\u0441\u044f \u0437 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0430\u043c\u0438 \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f<\/a><\/strong>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u0417\u0430 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0430\u043c\u0438 \u043f\u0456\u043b\u043e\u0442\u043d\u043e\u0433\u043e \u0434\u043e\u0441\u043b\u0456\u0434\u0436\u0435\u043d\u043d\u044f, \u0441\u0442\u043e\u0432\u0431\u0443\u0440\u043e\u0432\u0456 \u043a\u043b\u0456\u0442\u0438\u043d\u0438 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