{"id":10113,"date":"2019-02-25T11:03:51","date_gmt":"2019-02-25T11:03:51","guid":{"rendered":"https:\/\/futurehealthbiobank.com\/vn\/?p=10113"},"modified":"2021-08-31T12:28:09","modified_gmt":"2021-08-31T11:28:09","slug":"lap-trinh-te-bao-goc-de-san-xuat-insulin-cho-benh-tieu-duong-tuyp-1","status":"publish","type":"post","link":"https:\/\/futurehealthbiobank.com\/vn\/blog\/lap-trinh-te-bao-goc-de-san-xuat-insulin-cho-benh-tieu-duong-tuyp-1\/","title":{"rendered":"L\u1eadp tr\u00ecnh T\u1ebf b\u00e0o g\u1ed1c \u0111\u1ec3 s\u1ea3n xu\u1ea5t Insulin cho b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1"},"content":{"rendered":"

L\u1ea7n \u0111\u1ea7u ti\u00ean, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 bi\u1ebfn \u0111\u1ed5i t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a con ng\u01b0\u1eddi th\u00e0nh t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t insulin tr\u01b0\u1edfng th\u00e0nh. B\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 c\u00f3 th\u1ec3 \u0111\u01b0a ch\u00fang ta ti\u1ebfn m\u1ed9t b\u01b0\u1edbc g\u1ea7n h\u01a1n \u0111\u1ebfn vi\u1ec7c ph\u00e1t tri\u1ec3n ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1.<\/h3>\n

<\/p>\n

Insulin ch\u1ecbu tr\u00e1ch nhi\u1ec7m \u0111i\u1ec1u ch\u1ec9nh l\u01b0\u1ee3ng glucose v\u00e0 l\u01b0\u1ee3ng \u0111\u01b0\u1eddng trong m\u00e1u. Nh\u01b0ng c\u00e1c t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t insulin c\u1ee7a tuy\u1ebfn t\u1ee5y b\u1ecb ph\u00e1 h\u1ee7y \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng T1, g\u00e2y ra m\u1ed9t lo\u1ea1t c\u00e1c bi\u1ebfn ch\u1ee9ng mi\u1ec5n d\u1ecbch v\u00e0 th\u1eadm ch\u00ed t\u1ed5n th\u01b0\u01a1ng c\u01a1 quan nghi\u00eam tr\u1ecdng, ch\u1eb3ng h\u1ea1n nh\u01b0 suy th\u1eadn ho\u1eb7c \u0111\u1ed9t qu\u1ef5. Kh\u00f4ng c\u00f3 g\u00ec ng\u1ea1c nhi\u00ean khi c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng \u0111ang c\u1ed1 g\u1eafng t\u00e1i t\u1ea1o nh\u1eefng t\u1ebf b\u00e0o v\u00f4 c\u00f9ng quan tr\u1ecdng n\u00e0y trong ph\u00f2ng th\u00ed nghi\u1ec7m.<\/p>\n

Tr\u01b0\u1edbc \u0111\u00e2y, c\u00e1c nh\u00e0 khoa h\u1ecdc \u0111\u00e3 kh\u00f4ng th\u00e0nh c\u00f4ng trong vi\u1ec7c l\u1eadp tr\u00ecnh c\u00e1c t\u1ebf b\u00e0o g\u1ed1c th\u00e0nh c\u00e1c t\u1ebf b\u00e0o beta tr\u01b0\u1edfng th\u00e0nh ho\u00e0n to\u00e0n, khi\u1ebfn ch\u00fang kh\u00f4ng th\u1ec3 \u0111\u00e1p \u1ee9ng \u0111\u00fang c\u00e1ch v\u1edbi glucose trong m\u00e1u v\u00e0 ti\u1ebft ra insulin. Tuy nhi\u00ean, c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1i \u0110\u1ea1i h\u1ecdc California San Francisco \u0111\u00e3 t\u00ecm ra gi\u1ea3i ph\u00e1p. H\u1ecd \u0111\u00e3 nu\u00f4i c\u1ea5y c\u00e1c t\u1ebf b\u00e0o g\u1ed1c \u0111a n\u0103ng trong m\u1ed9t chi\u1ebfc \u0111\u0129a, s\u1eed d\u1ee5ng m\u1ed9t quy tr\u00ecnh ch\u01b0a t\u1eebng \u0111\u01b0\u1ee3c th\u1eed nghi\u1ec7m tr\u01b0\u1edbc \u0111\u00e2y.<\/p>\n

Nguy\u00ean l\u00fd ch\u00ednh trong sinh h\u1ecdc l\u00e0 s\u1ef1 bi\u1ec3u hi\u1ec7n ch\u1ee9c n\u0103ng, do \u0111\u00f3 ch\u00fang t\u00f4i tin r\u1eb1ng s\u1ef1 t\u1ea1o th\u00e0nh c\u00e1c c\u1ee5m l\u00e0 qu\u00e1 tr\u00ecnh quan tr\u1ecdng \u0111\u1ec3 c\u00e1c beta tr\u01b0\u1edfng th\u00e0nh.<\/p><\/blockquote>\n

‘- Gopika Nair, Ti\u1ebfn s\u0129, Trung t\u00e2m Ti\u1ec3u \u0111\u01b0\u1eddng UCSF<\/cite><\/p>\n

B\u1eb1ng c\u00e1ch t\u00e1ch nh\u00e2n t\u1ea1o c\u00e1c t\u1ebf b\u00e0o g\u1ed1c tuy\u1ebfn t\u1ee5y v\u00e0 bi\u1ebfn \u0111\u1ed5i ch\u00fang th\u00e0nh c\u00e1c c\u1ee5m gi\u1ed1ng nh\u01b0 \u0111\u1ea3o nh\u1ecf, s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a t\u1ebf b\u00e0o s\u1ebd t\u0103ng v\u1ecdt. Ch\u00fang ph\u1ea3n \u1ee9ng v\u1edbi \u0111\u01b0\u1eddng trong m\u00e1u v\u00e0 s\u1ea3n xu\u1ea5t insulin trong v\u00f2ng v\u00e0i ng\u00e0y – gi\u1ed1ng nh\u01b0 c\u00e1c t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t insulin tr\u01b0\u1edfng th\u00e0nh – theo c\u00e1ch ch\u01b0a t\u1eebng th\u1ea5y trong ph\u00f2ng th\u00ed nghi\u1ec7m.<\/p>\n

Hi\u1ec7n c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u t\u1ea1i UCSF \u0111ang nghi\u00ean c\u1ee9u c\u00e1c li\u1ec7u ph\u00e1p t\u00e1i t\u1ea1o cho b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1 b\u1eb1ng c\u00e1ch s\u1eed d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o g\u1ed1c n\u00e0y, hy v\u1ecdng s\u1ebd lo\u1ea1i b\u1ecf nhu c\u1ea7u c\u1ea5y gh\u00e9p tuy\u1ebfn t\u1ee5y. Ch\u1ec9 c\u00f3 1000 li\u1ec1u c\u00f3 th\u1ec3 cung c\u1ea5p h\u00e0ng n\u0103m cho h\u01a1n 1.5 tri\u1ec7u ng\u01b0\u1eddi mang b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1 t\u1ea1i M\u1ef9. Nair cho bi\u1ebft:<\/p>\n

C\u00e1c ph\u01b0\u01a1ng ph\u00e1p tr\u1ecb li\u1ec7u hi\u1ec7n t\u1ea1i nh\u01b0 ti\u00eam insulin ch\u1ec9 \u0111i\u1ec1u tr\u1ecb c\u00e1c tri\u1ec7u ch\u1ee9ng c\u1ee7a b\u1ec7nh\u2026 K\u1ebft qu\u1ea3 n\u00e0y cho th\u1ea5y m\u1ed9t s\u1ed1 ph\u01b0\u01a1ng th\u1ee9c th\u00fa v\u1ecb v\u00e0 h\u1eefu hi\u1ec7u \u0111\u1ec3 t\u00ecm ra ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb d\u1ee9t \u0111i\u1ec3m.
\nCu\u1ed1i c\u00f9ng ch\u00fang t\u00f4i c\u0169ng c\u00f3 th\u1ec3 ti\u1ebfp t\u1ee5c th\u1ef1c hi\u1ec7n m\u1ed9t s\u1ed1 d\u1ef1 \u00e1n tr\u01b0\u1edbc \u0111\u00e2y \u0111\u00e3 bu\u1ed9c ph\u1ea3i d\u1eebng l\u1ea1i\u2026 Kh\u1ea3 n\u0103ng d\u01b0\u1eddng nh\u01b0 l\u00e0 v\u00f4 t\u1eadn.<\/p><\/blockquote>\n

T\u00e0i li\u1ec7u tham kh\u1ea3o: https:\/\/www.ucsf.edu\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

L\u1ea7n \u0111\u1ea7u ti\u00ean, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 bi\u1ebfn \u0111\u1ed5i t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a con ng\u01b0\u1eddi th\u00e0nh t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t insulin tr\u01b0\u1edfng th\u00e0nh. B\u01b0\u1edbc \u0111\u1ed9t ph\u00e1 c\u00f3 th\u1ec3 \u0111\u01b0a ch\u00fang ta ti\u1ebfn m\u1ed9t b\u01b0\u1edbc g\u1ea7n h\u01a1n \u0111\u1ebfn vi\u1ec7c ph\u00e1t tri\u1ec3n ph\u01b0\u01a1ng ph\u00e1p ch\u1eefa b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1.<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[220],"tags":[],"class_list":["post-10113","post","type-post","status-publish","format-standard","hentry","category-clinical-updates"],"acf":[],"yoast_head":"\nStem Cells Engineered To Produce Insulin For Type 1 Diabetes | Future Health Biobank<\/title>\n<meta name=\"description\" content=\"For the first time, researchers have transformed human stem cells into mature insulin-producing cells. The breakthrough could lead us a step closer to developing a cure for Type 1 diabetes.\" \/>\n<meta name=\"robots\" content=\"noindex, follow\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L\u1eadp tr\u00ecnh T\u1ebf b\u00e0o g\u1ed1c \u0111\u1ec3 s\u1ea3n xu\u1ea5t Insulin cho b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 1\" \/>\n<meta property=\"og:description\" content=\"L\u1ea7n \u0111\u1ea7u ti\u00ean, c\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 bi\u1ebfn \u0111\u1ed5i t\u1ebf b\u00e0o g\u1ed1c c\u1ee7a con ng\u01b0\u1eddi th\u00e0nh t\u1ebf b\u00e0o s\u1ea3n xu\u1ea5t insulin tr\u01b0\u1edfng th\u00e0nh. 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