{"id":9017,"date":"2018-05-14T15:35:07","date_gmt":"2018-05-14T14:35:07","guid":{"rendered":"https:\/\/futurehealthbiobank.com\/vn\/?p=9017"},"modified":"2021-08-31T12:47:55","modified_gmt":"2021-08-31T11:47:55","slug":"te-bao-nk-cac-te-bao-sat-thu-tu-nhien-co-nguon-goc-tu-te-bao-goc-mau-day-ron-co-loi-cho-benh-nhan-benh-bach-cau-cap-dong-tuy","status":"publish","type":"post","link":"https:\/\/futurehealthbiobank.com\/vn\/blog\/te-bao-nk-cac-te-bao-sat-thu-tu-nhien-co-nguon-goc-tu-te-bao-goc-mau-day-ron-co-loi-cho-benh-nhan-benh-bach-cau-cap-dong-tuy\/","title":{"rendered":"T\u1ebf b\u00e0o NK (c\u00e1c t\u1ebf b\u00e0o s\u00e1t th\u1ee7 t\u1ef1 nhi\u00ean) c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb t\u1ebf b\u00e0o g\u1ed1c m\u00e1u d\u00e2y r\u1ed1n c\u00f3 l\u1ee3i cho b\u1ec7nh nh\u00e2n b\u1ec7nh b\u1ea1ch c\u1ea7u c\u1ea5p d\u00f2ng t\u1ee7y"},"content":{"rendered":"<h3>Acute Myeloid Leukaemia (AML) is a prevalent type of cancer in older adults. N\u00f3 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng h\u00f3a tr\u1ecb chuy\u00ean s\u00e2u v\u00e0 c\u00e1c h\u00ecnh th\u1ee9c ch\u0103m s\u00f3c h\u1ed7 tr\u1ee3 d\u1eabn \u0111\u1ebfn 40-60% b\u1ec7nh nh\u00e2n thuy\u00ean gi\u1ea3m ho\u00e0n to\u00e0n; lo\u1ea1i b\u1ecf c\u00e1c d\u1ea5u hi\u1ec7u c\u1ee7a b\u1ec7nh ung th\u01b0. Tuy nhi\u00ean, h\u1ea7u h\u1ebft b\u1ec7nh nh\u00e2n \u0111\u1ec1u t\u00e1i ph\u00e1t v\u1edbi t\u1ef7 l\u1ec7 s\u1ed1ng s\u00f3t sau 5 n\u0103m l\u00e0 kho\u1ea3ng 10%.<\/h3>\n<p><!--more--><\/p>\n<p>L\u1ea7n \u0111\u1ea7u ti\u00ean, T\u1ebf b\u00e0o g\u1ed1c v\u00e0 T\u1ebf b\u00e0o g\u1ed1c t\u1ea1o m\u00e1u (HSPC) t\u1eeb m\u00e1u d\u00e2y r\u1ed1n t\u01b0\u01a1ng th\u00edch HLA m\u1ed9t ph\u1ea7n \u0111\u00e3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 t\u1ea1o ra c\u00e1c t\u1ebf b\u00e0o NK. C\u00e1c t\u1ebf b\u00e0o NK n\u00e0y \u0111\u00e3 \u0111\u01b0\u1ee3c ch\u1ee9ng minh l\u00e0 c\u00f3 th\u1ec3 t\u1ea1m th\u1eddi kh\u00f4i ph\u1ee5c ch\u1ee9c n\u0103ng h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc b\u1ec7nh b\u1ea1ch c\u1ea7u c\u1ea5p d\u00f2ng t\u1ee7y v\u00e0 ng\u0103n ng\u1eeba t\u00e1i ph\u00e1t.<\/p>\n<p>C\u00e1c t\u1ebf b\u00e0o NK c\u00f3 ngu\u1ed3n g\u1ed1c t\u1eeb HSPC \u0111\u00e3 \u0111\u01b0\u1ee3c chuy\u1ec3n cho 10 b\u1ec7nh nh\u00e2n AML l\u1edbn tu\u1ed5i h\u01a1n sau khi h\u1ecd \u0111\u01b0\u1ee3c h\u00f3a tr\u1ecb li\u1ec7u gi\u1ea3m b\u1ea1ch huy\u1ebft. Trong v\u00f2ng v\u00e0i ng\u00e0y, c\u00e1c t\u1ebf b\u00e0o NK \u0111\u01b0\u1ee3c truy\u1ec1n v\u00e0o c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n c\u00f3 d\u1ea5u hi\u1ec7u tr\u01b0\u1edfng th\u00e0nh v\u00e0 ph\u00e2n b\u1ed5 trong c\u01a1 th\u1ec3 b\u1ec7nh nh\u00e2n. \u1ede b\u1ec7nh nh\u00e2n, c\u00e1c t\u1ebf b\u00e0o NK \u0111\u00e3 l\u00e0m t\u0103ng th\u00e0nh c\u00f4ng m\u1ee9c \u0111\u1ed9 c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 huy\u1ebft t\u01b0\u01a1ng v\u00e0 c\u00e1c ch\u1ec9 s\u1ed1 v\u1ec1 ch\u1ee9c n\u0103ng mi\u1ec5n d\u1ecbch b\u00ecnh th\u01b0\u1eddng. \u0110\u00e1ng ng\u1ea1c nhi\u00ean l\u00e0 m\u1ed9t s\u1ed1 b\u1ec7nh nh\u00e2n c\u00f3 m\u1ee9c c\u00f2n b\u1ec7nh t\u1ed1i thi\u1ec3u (Minimum Residual Disease MRD) trong t\u1ee7y x\u01b0\u01a1ng tr\u01b0\u1edbc khi ti\u00eam truy\u1ec1n tr\u1edf n\u00ean \u00e2m t\u00ednh v\u1edbi MRD trong m\u1ed9t th\u1eddi gian d\u00e0i sau khi truy\u1ec1n. Nh\u1eefng k\u1ebft qu\u1ea3 n\u00e0y mang l\u1ea1i hy v\u1ecdng cho vi\u1ec7c s\u1eed d\u1ee5ng t\u1ebf b\u00e0o g\u1ed1c m\u00e1u d\u00e2y r\u1ed1n trong ph\u00e1t tri\u1ec3n li\u1ec7u ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0.<\/p>\n<p>Th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng do c\u00e1c nh\u00e0 khoa h\u1ecdc t\u1ea1i Hi\u1ec7p h\u1ed9i Nghi\u00ean c\u1ee9u Ung th\u01b0 M\u1ef9 th\u1ef1c hi\u1ec7n v\u00e0 \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 v\u00e0o th\u00e1ng 3\/2017.Nh\u1eefng ph\u00e1t hi\u1ec7n \u0111\u1ea7y h\u1ee9a h\u1eb9n cho th\u1ea5y r\u1eb1ng c\u00e1c t\u1ebf b\u00e0o HSPC-NK c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong t\u01b0\u01a1ng lai nh\u01b0 m\u1ed9t d\u1ea1ng li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch \u201cc\u00f3 s\u1eb5n\u201d cho nh\u1eefng ng\u01b0\u1eddi s\u1ed1ng chung v\u1edbi AML.<\/p>\n<p>M\u1eb7c d\u00f9 c\u00e1ch ti\u1ebfp c\u1eadn \u0111\u01b0\u1ee3c m\u00f4 t\u1ea3 \u1edf tr\u00ean l\u00e0 m\u1ed9t b\u01b0\u1edbc ti\u1ebfn tuy\u1ec7t v\u1eddi trong vi\u1ec7c k\u00e9o d\u00e0i s\u1ef1 s\u1ed1ng \u1edf b\u1ec7nh nh\u00e2n AML, nh\u01b0ng n\u00f3 v\u1eabn c\u1ea7n \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u th\u00eam v\u1ec1 kh\u1ea3 n\u0103ng ti\u00eau di\u1ec7t t\u1ebf b\u00e0o kh\u1ed1i u.<br \/>\nSource:\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28280089\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/28280089<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Acute Myeloid Leukaemia (AML) is a prevalent type of cancer in older adults. N\u00f3 hi\u1ec7n \u0111ang \u0111\u01b0\u1ee3c \u0111i\u1ec1u tr\u1ecb b\u1eb1ng h\u00f3a tr\u1ecb chuy\u00ean s\u00e2u v\u00e0 c\u00e1c h\u00ecnh th\u1ee9c ch\u0103m s\u00f3c h\u1ed7 tr\u1ee3 d\u1eabn \u0111\u1ebfn 40-60% b\u1ec7nh nh\u00e2n thuy\u00ean gi\u1ea3m ho\u00e0n to\u00e0n; lo\u1ea1i b\u1ecf c\u00e1c d\u1ea5u hi\u1ec7u c\u1ee7a b\u1ec7nh ung th\u01b0. Tuy nhi\u00ean, h\u1ea7u h\u1ebft b\u1ec7nh [&hellip;]<\/p>\n","protected":false},"author":18,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[220],"tags":[],"class_list":["post-9017","post","type-post","status-publish","format-standard","hentry","category-clinical-updates"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v26.7 (Yoast SEO v26.7) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Cord Blood Stem Cell Derived \u2018Natural Killer\u2019 Cells Benefit Acute Myeloid Leukaemia Patients | Future Health Biobank<\/title>\n<meta name=\"description\" content=\"For the first time, Hematopoietic Stem and Progenitor Cells (HSPCs) from partially HLA-matched umbilical cord blood have been used to generate Natural Killer (NK) cells. 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